Next Generation Sequencing Bioinformatics

The programme will cover the algorithmic theory and principles of bioinformatics, with a strong focus on practical computational sessions using sequence analysis techniques and tools applicable to any species or genome size. Accompanying the lecture and practical sessions will be a series of seminars by invited speakers, who will highlight their ground-breaking work in applications of next generation sequencing.

The hands-on programme will cover several aspects of next generation sequencing data analysis, including lectures, discussions and practical computational sessions covering the following:
- Introduction to NGS technologies and tour of Sanger Institute facilities
- Introduction to the unix command line
- Introduction to scripting for bioinformatics
- NGS data formats and tools
- Sequence alignment+QC
- SNP/indel theory and practical
- Structural variation theory and practical
- De novo sequence assembly
- RNA-seq analysis
- ChiP-seq analysis
- Sequencing data visualisation with the Integrated Genomics Viewer
- Accessing public sequencing repositories
- Participant projects and presentations (final day)

Please note: The practical sessions will be taught exclusively through Unix/Linux. Therefore, participants are required to have some previous exposure of using the Linux operating system. This will be essential for participants to fully benefit from the course.

Category: Conferences, Science, Health and Medicine, Biology, Computational Biology

Price:
Non-commercial residential course fee: GBP 665

Speakers: Thomas Keane (Wellcome Trust Sanger Institute, UK), Jacqui Keane (Wellcome Trust Sanger Institute, UK), Mary O'Connell (University of Leeds, UK), Clare Smith (University of Massachusetts Medical School, USA), Aylwyn Scally (University of Cambridge, UK), Stephen Bentley (Wellcome Trust Sanger Institute, UK)